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This research suggests that degron loss is a general mechanism in tumorigenesis, similar to promoter swapping, as shown in the study's PDF document .

9,624 tumor samples from TCGA, investigating degron loss (a mechanism that stabilizes proteins, encouraging cancer growth). Key Findings: 24336.rar

Specific recurrent fusions validated included BCR-ABL, CCDC6-RET, and PML-RARA. This research suggests that degron loss is a