Official Adobe Creative Suite 6 was never updated to a "2022 version." Downloads labeled as such are typically unofficial repackages (like Adobe Master Collection CC 2022) that bundle newer Creative Cloud apps with a custom installer, or pirated versions of the 2012 suite.
For professional workflows, Adobe recommends the Creative Cloud to ensure compatibility with modern hardware and file formats. Master Collection CS6 Max License Issue - Adobe Community adobe-master-collection-cs6-full-version-2022
Provides native 64-bit support in Photoshop, Illustrator, Premiere Pro, and After Effects, allowing the software to utilize more RAM for complex projects. Official Adobe Creative Suite 6 was never updated
While it may still run on Windows 10 or 11, users often report installation errors, activation server failures, and UI scaling issues on high-resolution displays. It is largely incompatible with modern macOS versions (macOS 10.15 Catalina and later) because those systems do not support older 32-bit components. While it may still run on Windows 10
Features like "Liquid Layout" in InDesign allow designers to create content for multiple screen sizes and orientations. Compatibility and Support in 2022+