Cash App is one of the few platforms that occasionally allows linking certain prepaid cards, though it is hit-or-miss with Amex Serve.

Buying Bitcoin directly with an prepaid card is tricky because major exchanges like Coinbase and CEX.IO generally do not support American Express or prepaid cards for direct crypto purchases.

Buying with prepaid cards is one of the most expensive ways to get Bitcoin due to high "convenience" markups and potential cash advance fees.

Fees on P2P platforms for prepaid cards can be very high, sometimes up to 30% above market price. 2. Cash App (US Only)

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The BitPay app allows you to buy crypto via third-party partners like MoonPay or Simplex. While they rarely accept Amex prepaid cards directly, you can sometimes use them through or Google Pay if those wallets accept your Amex Serve card. Key Things to Watch Out For:

This is the most reliable method for using an Amex Serve card. You aren't buying from the exchange itself, but from a private seller who accepts Serve transfers.

Search for sellers who accept "American Express Serve" or "Amex Serve to Serve" transfers.