: Activated JAKs phosphorylate the receptor tail, creating docking sites.
: Phosphorylated STATs dissociate and form dimers. Download Les inhibiteurs JAK STAT pdf
: STAT dimers translocate to the nucleus to regulate gene expression. Basic Mechanisms of JAK Inhibition - PMC - NIH : Activated JAKs phosphorylate the receptor tail, creating
: Phosphorylated STATs dissociate and form dimers.
: STAT dimers translocate to the nucleus to regulate gene expression. Basic Mechanisms of JAK Inhibition - PMC - NIH
