Grey's Anatomy S16e16 May 2026

He apologizes for leaving via a letter and reveals he is filing for divorce. He leaves her his shares in Grey Sloan Memorial Hospital.

Season 16, Episode 16 of Grey's Anatomy , titled serves as the official farewell to original cast member Justin Chambers , who played Dr. Alex Karev . The episode aired on March 5, 2020, and is one of the most controversial in the series' history due to how it handles Alex's departure. ✉️ The Core Format: Letters from Alex Grey's Anatomy s16e16

He discovered that Izzie used the embryos they froze years ago when she had cancer. He apologizes for leaving via a letter and

Alex claims that while he still loves Jo , he cannot bear to let his children grow up without a father the way he did. He is now living on a farm in Kansas where Izzie works as a surgical oncologist. ⚡ Secondary Storylines Alex Karev

He expresses his gratitude for their mentorship over the years. The Big Reveal: Izzie Stevens and the Twins