Gtlela
: Despite being an insect, its innate immune system shows remarkable similarities to that of mammals, including specialized cells (hemocytes) that function like human neutrophils.
: It allows researchers to follow the "3Rs" principle (Replacement, Reduction, and Refinement) by replacing vertebrate animals in early-stage studies. Gtlela
: Because these larvae were historically sold as reptile food, recent research focuses on standardizing laboratory breeding to ensure reproducible results across different global labs. : Despite being an insect, its innate immune
: Unlike many other invertebrates, these larvae can survive at 37°C , which is the human body temperature, making them ideal for studying human pathogens like Candida albicans or Staphylococcus aureus . : Despite being an insect
: They are inexpensive, easy to handle, and produce results within days rather than weeks. Recent Research Directions