When things go wrong, TG2 shifts roles. In the extracellular space, it binds to integrins and acts as a co-receptor, facilitating cell adhesion and migration.
TG2 acts as a "molecular glue," crosslinking extracellular collagen and fibronectin to help stabilize tissue structure, making it vital for wound healing. When things go wrong, TG2 shifts roles
🔬 TG2: The Molecular "Swiss Army Knife" Shaping Cellular Fate When things go wrong
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